Atherosclerosis is also a chronic inflammatory disease, as an inflammatory response accompanies its onset.180 Macrophages are one of the cells responsible for atherosclerosis; they form foam cells by phagocytosing lipid droplets and accelerating the progression of atherosclerosis.181,182 Basu et al.183 reported that macrophage-specific deletion of RPL13 increases the susceptibility of ApoE knockout mice to high-fat diet-induced atherosclerosis. This evidence concerns the gene RPL13 and atherosclerosis.