在NSCLC中,与CD8+CD103-肿瘤浸润淋巴细胞(tumor infiltrating lymphocytes, TILs)相比,CD8+ TRM高度表达CD39[35]。在转移性淋巴结中也检测到CD39+CD8+ TRM,但在非肿瘤累及的淋巴结或循环血中并未检测到,表明CD39+CD8+ TRM是区分肿瘤的特异性标志[36]。. The gene discussed is ITGAE; the disease is neoplasm.