However, studies addressing HER2/neu expression in patients with lung cancer have only included patients with one specific type of cancer, such as adenocarcinoma,12 and other types of NSCLC,13, 14 mainly with small sample size; and the prognostic value of HER2/neu overexpression in different lung cancer types has to be yet determined.15, 16. This evidence concerns the gene ERBB2 and cancer.