The cytokine concentration in joints from mice with experimental RA is shown in Figure 5; the damaged group (Veh) presented a significant increase in IL-17, IL-1β, IL-6, and TNF-α, with 2-, 13-, 12-, and 3-fold increases, respectively, in comparison with the basal group (* p < 0.05). The gene discussed is IL1B; the disease is rheumatoid arthritis.