After LPS induction, supernatant IL-6 (p = 0.005), IL-8 (p = 0.01), IL-10 (p = 0.001), and MCP-1 (p = 0.029) at 24 h and IL-8 (p = 0.015), IL-10 (p < 0.001), and MCP-1 (p < 0.001) at 48 h were higher in SIRS compared to healthy control and/or sepsis (Table 5). This evidence concerns the gene CXCL8 and systemic inflammatory response syndrome.