Idborg [103] stratified patients with SLE according to their autoantibody profile in two subgroups, those with Sjögren’s syndrome-like SLE (the SSA/SSB+ group, where they were all positive for all three of SSA and SSB antibodies, though negative in the lupus anticoagulant (LA)) and those with antiphospholipid syndrome-like SLE (the aPL+ group, all positive in the LA test, but negative for all three of SSA and SSB antibodies). This evidence concerns the gene SSB and antiphospholipid syndrome.