Moreover, it showed a strong inhibitory effect on the expression of several proinflammatory cytokines (IL-8, interleukin 12 (IL-12), interleukin 17 (IL-17), interleukin 22 (IL-22), and interleukin 23 (IL-23)) in vitro, in LPS-stimulated human THP-1 leukemia monocytes [151]. The gene discussed is IL22; the disease is leukemia.