Tung et al. found an association between high levels of brain natriuretic peptide (BNP) and soluble suppression of tumorigenicity-2 (sST2), as well as biomarkers of renal injury, i.e., NGAL and cystatin C, and the risk of AKI in STEMI patients undergoing PCI. The gene discussed is NPPB; the disease is acute kidney injury.