Both T1 and T3 tumours overexpressed the monocarboxylic transporter 4 (MCT4) (data not shown) for lactate export, whereas T3 vs. T1 tumours specifically up regulated transcript expression of monocarboxylic transporter 1 (MCT1) for lactate import and lactate dehydrogenase A (LDHA) for lactate metabolism (Figure 4A). The gene discussed is SLC16A3; the disease is neoplasm.