Application of 25 μM α-13’-COOH significantly reduced the secretion of IL-8 in atopic dermatitis skin models m2 (0.6 ± 0.03-fold, p < 0.001; Figure 8b) and m3 (0.6 ± 0.02-fold, p < 0.001; Figure 8b) at days 9 to 12 compared to the disease control, similar to dexamethasone (m2: 0.6 ± 0.03-fold, p < 0.001; m3: 0.5 ± 0.07-fold, p < 0.001; Figure 8b). This evidence concerns the gene CXCL8 and atopic eczema.