In accordance with the results of the mRNA expression obtained for primary keratinocytes (Figure 2a), atopic dermatitis biomarkers such as NELL2, CA2 and CCL26 were significantly elevated in skin models m2 and m3 stimulated with TH2 cytokines (p < 0.05, p < 0.001, respectively; Figure 4b). The gene discussed is CA2; the disease is atopic eczema.