Moreover, a markedly significant increase in the inflammatory marker of atopic dermatitis severity, namely IL-8, was found after 1 h (7.7 ± 2.6-fold, p < 0.01; Figure 2c) 24 h (13.1 ± 2.3-fold, p < 0.001; Figure 2c) and 48 h (5.2 ± 0.3-fold, p < 0.001; Figure 2c) of incubation with the combination of TH2 cytokines and histamine. This evidence concerns the gene CXCL8 and atopic eczema.