NDRG1 and gastric cancer: It was also found that deferasirox induces apoptosis and upregulates N-myc downstream regulated gene 1 (NDRG1) [111], which plays an important role in cancer progression by inhibiting metastasis [277], and downregulates phospho-mTOR and c-myc expression, showing that this drug exhibits antitumour effects on GC cells through different pathways [111].