PSMB6 and rheumatoid arthritis: RA pathogenesis is characterized by an imbalance between anti-inflammatory and proinflammatory cytokines (interleukin (IL)-1β, tumor necrosis factor-α (TNF-α), interferon (IFN)-y, IL-6, IL-12, and IL-17), all playing a significant role in the inflammatory processes involved in the pathology [56,57,58].