In turn, the NEP protein level and activity were unaffected, i.e., neither down- nor upregulated, by the AKG treatment in the other cancer cells, i.e., SiHa (Figure 2a,g), CaSki (Figure 2b,h), SW948 (Figure 2a,e), SW620 (Figure 2b,f), and Saos-2 (Figure 2c,g). This evidence concerns the gene MME and cancer.