CRP and ulcer disease: Regarding the relationship between inflammatory markers and healing time in patients with DFO, a paper [23] whose objective was to analyse the predictive role of leukocytes, ESR and CRP, in the healing time of DFO treated by surgery or antibiotics concluded that there is not enough evidence to define the prognostic role of these inflammatory markers in the healing time of ulcers complicated with DFO, regardless of the treatment administered.