Surprisingly, the best known CFH variant with a strong reported association to AMD (rs1061170) was not included in the model and was rejected at the clumping step on behalf of other variants in the CFH locus with a higher impact on AMD in the analysed cohorts (possibly on behalf of rs2274700, as Maller, Li and Francis confirmed the stronger association of that variant to AMD [49,52,53]). This evidence concerns the gene CFH and age-related macular degeneration.