Among the 837 EGFR-mutant tumor samples, 633 (75.6%) harbored classical EGFR mutations, including Ex19del (32.4%, n = 271), L858R (27.2%, n = 228), Ex19del/L858R concomitant with T790M (15.5%, n = 130), and T790M alone (0.5%, n = 4) (Figure 2a). This evidence concerns the gene EGFR and neoplasm.