CEACAM5 and neoplasm: Previous retrospective studies reported various possible prognostic factors including CA19-9, gross appearance, tumor size, tumor invasion, lymph node metastases, TNM stage, lymphovascular invasion, perineural invasion, positive margin, poor differentiation, tumor markers (CEA and CA19-9), high lactate dehydrogenase, symptoms at diagnosis, and old age [10,11,12,13].