Finally, we performed a multivariate analysis including TNM stage, which is considered an essential factor related to patient survival clinically, and discovered that both KLF6 expression (HR = 2.254, p = 0.033) and tumor grade (HR = 2.313, p = 0.026) were informative as prognostic markers for clinical outcome in patients (Table 3), indicating that KLF6 may be a potential prognosticator of PAAD prognosis. The gene discussed is KLF6; the disease is pancreatic adenocarcinoma.