In recent years, molecular detection of glioma has achieved a certain degree of development, including MGMT promoter methylation, co-deletion of 1p/19q, IDH mutation, TERT promoter mutation, EGFR amplification, etc. This molecular information plays an important role in the prognosis and treatment of glioma [24,25,26]. The gene discussed is MGMT; the disease is central nervous system cancer.