MMP-7 is likely to be associated with adhesion, as the downregulation of MMP-7 could suppress invasion without influencing proliferation; it also takes part in serosal involvement, lymph node metastasis, poor differentiation of cancer and peritoneal dissemination, indicating its role in peritoneal adhesion [53]. This evidence concerns the gene MMP7 and metastatic malignant neoplasm in the lymph nodes.