LEP and obstructive sleep apnea syndrome: There is a moderate level of evidence that OSA is associated with increased levels of serum and plasma inflammatory cytokines, oxidative stress indicators, adhesion molecules, adipose tissue hormones, abnormal lipid profile, and elevated liver enzymes, which can be decreased with CPAP treatment, namely, CRP, IL-6, TNF-α, Il-8, HCY, ICAM-1, VCAM-1, VEGF, TC, LDLc, HDLc, TG, leptin, adiponectin, cortisol, MDA, ALT, AST, and IGF-1.