The duration of diabetes (p = 0.81), vascular complications (p = 0.22), in each trimester additionally: HbA1c (p = 0.47; p = 0.97; p = 0.81, respectively), triglycerides (p = 0.49; p = 0.46; p = 0.21, respectively), protein loss within 24 h of urine collection (p = 0.74; p = 0.85; p = 0.67, respectively), creatinine clearance (p = 0.19; p = 0.59; p = 0.5, respectively), and serum creatinine concentration (p = 0.73; p = 0.94; p = 0.82 respectively) were considered as the potential determinants of corin concentration, although none of the above affected protease concentration. This evidence concerns the gene CORIN and diabetes mellitus.