In particular, the Dwass–Steel–Critchlow–Fligner test for pairwise comparisons indicated that the MBP concentration was significantly lower in HC (median: 17.85 pg/mL, interquartile range (IQR): 14.00–24.39 pg/mL) compared to CIS (median: 78.73 pg/mL, IQR: 65.78–91.20 pg/mL; p < 0.001 vs. HC), RRMS (median: 83.76 pg/mL, IQR: 71.05–95.03 pg/mL; p < 0.001 vs. HC) and PPMS (median: 136.44 pg/mL, IQR: 86.32–225.67 pg/mL; p < 0.001 vs. HC) (Figure 2A). Here, MBP is linked to in situ carcinoma.