When MBP in ODEVs was analyzed in HC vs. MS patients (considering together CIS, RRMS, and PPMS) an ROC area under the curve (AUC) = 0.963 (0.916–0.988 95% confidence interval (CI)) with 97.84% sensitivity and 100.00% specificity (p < 0.0001) was obtained (Figure 3A). The gene discussed is MBP; the disease is in situ carcinoma.