Buscail et al. combined the diagnostic accuracy of circulating tumor cells (CTC—DAPI+, CK+, EpCAM+, and CD45−) or GPC1+ exosomes in peripheral and portal blood, reaching 45% (5/11) of accuracy in the identification of PDAC in portal blood and 10% (2/22) in peripheral blood. The gene discussed is GPC1; the disease is neoplasm.