TNNI3 and myocardial infarction: Furthermore, the term acute myocardial infarction (AMI) should be used when there is acute myocardial injury with clinical evidence of acute myocardial ischemia and with detection of a rise and/or fall of cTnI or cTnT values (preferentially measured with hs-cTn methods) with at least one value above the 99th percentile URL in the clinical setting of myocardial ischemia [250].