Furthermore, the ratio of the excess heat capacities of HSA and Igs transitions, cPHSA/cPIgs, varied considerably for PD and ALS cases, being drastically high for the PD1* case and for the ALS2 set, too low for the PD4* case, and in the range from 1.4–1.95 for most cases, due to different tendencies in the changes of cPHSA and cPIgs values (Table 1). Here, ALB is linked to amyotrophic lateral sclerosis.