CCL2 and neoplasm: While chronic inflammation promotes tumor progression, tumor cells themselves also attract immune cells via chemokines such as IL-8, CCL2 (MCP-1), CCL3 (MIP-1α), CCL5 (RANTES), CXCL6 (huGCP-2), and cytokines such as IL-1β, IL-6, TNFα, GM-CSF, and G-CSF, inducing inflammation [58].