PTPRC and neoplasm: Here, we assessed lymphocyte infiltrates in the tumor according to the gating strategy, as shown in Supplementary Figure S5, and observed a significant increase in the percentage of CTLs (5.2% of total CD45+ cells) and NK cells (3.7%) in HIF-1αΔNφ compared with littermate controls (3.3% and 1.4%, respectively) (Figure 7a,b).