Pancreatic tumor cells specifically over-express glycolytic enzymes, such as hexokinase 2 (HK2), pyruvate dehydrogenase kinase isozyme 1 (PDK1) and lactate dehydrogenase A and B (LDHA, LDHB) compared to normal pancreatic cells [4]. The gene discussed is HK2; the disease is pancreatic neoplasm.