PRKN and Parkinson disease: Namely, three dysregulated miRNAs (miR-34b, miR-218, and miR-221) interact with the PD-related genes parkinsonism associated deglycase (DJ1), parkin RBR E3 ubiquitin protein ligase (PRKN), and synuclein alpha (SNCA) and modulate their functions in different PD cellular and animal models.