TNF and migraine disorder: Interestingly, episodic migraine patients carrying the A allele of the TNF-α promoter −308 A/G polymorphism showed a significant association with a lack of efficacy after NSAID administration in migraine attacks compared to the G allele (chi-square: 8.527, p = 0.003, OR 2.51, 95% CI: 1.33 < OR < 4.75, NSAID non-responders vs. NSAID partial responders and responders; OR 2.31, 95% CI: 1.12 < OR < 4.81, NSAID non-responders vs. NSAID responders; OR 2.74, 95% CI: 1.29 < OR < 5.84, NSAID non-responders vs. NSAID partial responders).