Allergic asthma is one of the common comorbidities associated with AR and it has been shown that 21–27% of patients suffering from allergic asthma in combination with AR were IgE-sensitized against staphylococcal toxins such as staphylococcal enterotoxin A (SEA), SEB, or TSST-1 [96]. The gene discussed is IGHE; the disease is allergic asthma.