SDHD and neoplasm: The most frequent variant was a missense variant in the SDHD gene, NM_003002: c.A305G, p.H102R (chr11:111959726, rs104894302), which we detected in 14 tumor tissues obtained from 12 patients (1 patient had multifocal HNPGLs manifesting as two bilateral carotid PGLs and a vagal PGL (001tc1, 001tc2, and 001tv)) [12] (Table 2).