EDN1 and type 2 diabetes mellitus: Progressively increasing expression of miR-92a in serum from healthy individuals via T2DM to T2DM with CAD showed positive correlations with NF-κB p65 expression and the level of proinflammatory cytokines, including ET-1, MCP-1, and ICAM-1, in patients with T2DM and CAD [300].