For example, in human colon cancer cell lines SNU-C4, HT-29, and H508, administration of atropine, muscarinic receptors inhibitor eradicated SNU-C4 cell migration and HT-29 invasion; however, H508 cell migration entails the activation of MMP7 via EGFR and ERK signaling pathways [34,35]. The gene discussed is EGFR; the disease is colonic neoplasm.