Given the heightened levels of NK cells and CD8+ t cells in ALS patients [20], in association with elevations in IFN-γ, TNF-α, I, and IL-17a [20], is this indicative of increased IL-17 producing, as well as classical IFN-γ producing, NK cells and/or γδ17 t cells or Th17 cells? The gene discussed is TNF; the disease is amyotrophic lateral sclerosis.