It was earlier established that some DNA repair-related genes and their protein products are also engaged in various vascular-related processes, such as vascular endothelial growth factor A (VEGFA) function (RAD21) [31], muscle stem cell activation (DEK) [32], atherosclerosis (MORF4L2 [33], FZR1 [34]), neointimal formation (SIRT7) [35] and foam cell formation (USP10) [36], and have been associated with cardiovascular risk factors (TRRAP [37], NPAS2 [38]). The gene discussed is FZR1; the disease is atherosclerosis.