In addition, the lower expression of AGER1 in the skeletal muscle (Figure 12B), the lower MAPK, NF-κB, and AGER1 in the pancreas (Figure 12C), and the lower MAPK in the thymus were observed in STZ-induced T2DM rat group treated with DL-arginine (p < 0.05), (Figure 12D). The gene discussed is DDOST; the disease is type 2 diabetes mellitus.