Furthermore, the effects of DL-arginine on the inflammatory-related genes expression in the liver, skeletal muscle, pancreas, and thymus of STZ-induced T2DM rats were detected, including mitogen-activated protein kinase (MAPK), nuclear factor- κB (NF-κB), and AGE receptor 1 (AGER1). Here, NFKB1 is linked to type 2 diabetes mellitus.