DC/DCleu and their subtypes, e.g., DCleu, mature DC (DCmat) and mature leukemia-derived DC (DCleu-mat) (Table 1), can be generated from whole blood (WB) using selected combinations of response modifiers (e.g., GM-CSF (granulocyte macrophage colony-stimulating factor) + PGE1 (prostaglandin E1) (Kit-M) or GM-CSF+Picibanil (Kit-I)) without the induction of blast proliferation (as detected by blasts’ co-expression of transferrin receptor CD71 (Blaprol-CD71) or intracellular proliferation marker IPO38 (Blaprol-IPO38); see Table 1) [10,11,12,13]. Here, CSF2 is linked to leukemia.