A study by Nan et al. identified a novel marker, LOX-1 (lectin-like oxidized low-density lipoprotein (LDL) receptor-1) in PMN-MDSCs in HCC patients and found that LOX-1+CD15+ cells were increased in the peripheral blood and their frequencies were associated with those present in HCC tissue [69]. This evidence concerns the gene OLR1 and hepatocellular carcinoma.