PRKACB acts as an activator of the up-regulated calcium voltage-gated channel auxiliary subunit gamma 4 (CACNG4) gene in dilated cardiomyopathy (bta05414); the down-regulated gene glutamic-oxaloacetic transaminase 1 (GOT1) is associated with the down-regulated genes adenylosuccinate synthase (ADSS) and D-aspartate oxidase (DDO). The gene discussed is PRKACB; the disease is dilated cardiomyopathy.