In the analysis of transcriptome data from hypoxic and normoxic cultured human peripheral blood mononuclear cell (PBMC)-derived macrophages, it was found that C-X-C motif chemokine ligand 8 (CXCL8) expression was increased, and CXCL8 is reportedly involved in gastric cancer malignancy [35]. The gene discussed is CXCL8; the disease is gastric cancer.