Recently, a prognostic classifier of 10 mitochondrial-related genes was identified in hepatocellular carcinoma (HCC), including ACOT7, ADPRHL2, ATAD3A, BSG, FAM72A, PDK3, PDSS1, RAD51C, TOMM34, and TRMU) [13]. The gene discussed is PDK3; the disease is hepatocellular carcinoma.