FAM72A was significantly associated with the TMB in 18 cancer types, including ACC, BRCA, BLCA, COAD, HNSC, KICH, LGG, LUAD, LUSC, PAAD, PRAD, READ, sarcoma (SARC), SKCM, STAD, THCA, THYM, and UCEC (Figure 5A). The gene discussed is FAM72A; the disease is cancer.