CD8A and cutaneous melanoma: FAM72A exhibited positive associations with CD8+ T cells in ESCA, KIRC, LUAD, LUSC, skin cutaneous melanoma (SKCM), and THCA, negative associations with M2 macrophages in BRCA, KIRC, KIRP, LIHC, SKCM, THCA, THYM, and uterine carcinosarcoma (UCS), as well as negative associations with Treg cells in BLCA, CESE, COAD, DLBC, LAML, LUAD, LUSC, PRAD, SKCM, TGCT, and UCES (Figure 4B).