In addition, because the MDA-MB-231 cell line is intrinsically deficient in E-cadherin expression [26] and the slug protein acts as a promoting transcription factor capable of increasing vimentin in invasive and metastatic cancers [27], we examined whether UA reduces slug and vimentin levels to prohibit migration and invasion of both breast cancer cell lines. This evidence concerns the gene VIM and metastatic malignant neoplasm.