NFE2L2 and cancer: EGCG may act as a potent Nrf2 activator [166,173,174], and its favorable effects in cancer [125,126] or in cardiovascular [43,127,175], neurodegenerative [112,128,176], respiratory [177,178], or other diseases [179,180,181] mediated via activation of Nrf2 have been published in numerous articles.