BALF exosomes CF patients were enriched withproteins implicated in neutrophil function, such as chemotaxis (LCN2, S100A12) and degranulation (grancalcin), antioxidant proteins (SOD2, GPX3, PRDX5), antiproteases (SERPINAA6), and those involved in the response to the chronic infectious challenge (histones, TOLLIP). The gene discussed is TOLLIP; the disease is cystic fibrosis.