That altered Mg balance has a role in Parkinson’s disease is further supported by the evidence that mutations of the Mg transporting protein solute carrier family 41 member 1 (SLC41A1) were reported in familial Parkinson’s disease patients [105,106], and SLC41A1 downregulation occurs in a Parkinsonian animal model [107]. Here, SLC41A1 is linked to Parkinson disease.