Based on the study, DHM could active the AhR [45]; previously, we also found DHM can ameliorate the progression of liver fibrosis and inhibit HSC activation by inducing autophagy and enhancing NK cell-mediated killing through the AhR-NF-κβ/STAT3-IFN-γ signaling pathway, providing new insights into the preventive role of DHM in liver fibrosis [46]. Here, NFKB1 is linked to Hepatic fibrosis.