ZEB1 and posterior polymorphous corneal dystrophy: Genetic analysis of six genes associated with PPCD, included in a panel of 298 genes related to ophthalmological diseases, was conducted using the massive sequencing technique, which found the initiator codon variant ZEB1 (OMIM #189909): NM_030751.6:c.1A > C (p.Met1Leu) in heterozygosity, which was confirmed by Sanger sequencing (Figure 3).