MiR-155, a multifunctional miRNA, is involved in a number of activities that modify the immune response in tumour patients: it affects tumour cell proliferation, downregulates the expression of the immune response modulator SHIP1 resulting in induction of pro-inflammatory cytokine production, participates in the impaired development of immune cells (B and T lymphocytes, dendritic cells) and impairs their function (macrophages, mast cells) [90,91]. Here, INPP5D is linked to neoplasm.