Kidney biopsies from patients with FSGS, whose plasma induced perilipin-2 expression and lipid droplet formation in hPod (rec1 and nat1), were stained with anti-perilipin-2 antibody and compared to a healthy kidney and biopsies from patients with IgA nephropathy or membranous nephropathy (Figure 8). Here, PLIN2 is linked to focal segmental glomerulosclerosis.