HMGCR and hyperthyroidism: A total of 41 key genes, 100 potential targets, and 2 common targets were imported into Cytoscape to define the Gene Target-Prediction Target network and are shown in Figure 10A. FASN and HMGCR (found using an integrated transcriptomics analysis and network pharmacology approach) may play essential roles in the antioxidative mechanism of EEP in hyperthyroidism.